17 Chemistry and Biochemistry

Atoms First / OpenStax

Authors: Paul Flowers, Edward J. Neth, William R. Robinson, Klaus Theopold, and Richard Langley

Description: Chemistry: Atoms First 2e is a peer-reviewed, openly licensed introductory textbook produced through a collaborative publishing partnership between OpenStax and the University of Connecticut and UConn Undergraduate Student Government Association.This text is an atoms-first adaptation of OpenStax Chemistry 2e. The intention of “atoms-first” involves a few basic principles: first, it introduces atomic and molecular structure much earlier than the traditional approach, and it threads these themes through subsequent chapters. This approach may be chosen as a way to delay the introduction of material such as stoichiometry that students traditionally find abstract and difficult, thereby allowing students time to acclimate their study skills to chemistry. Additionally, it gives students a basis for understanding the application of quantitative principles to the chemistry that underlies the entire course. It also aims to center the study of chemistry on the atomic foundation that many will expand upon in a later course covering organic chemistry, easing that transition when the time arrives.

The second edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Substantial improvements have been made in the figures, illustrations, and example exercises that support the text narrative.

The Basics of General, Organic, and Biological Chemistry

This peer-reviewed open textbook was developed to suit a one-semester General, Organic and Biological Chemistry course.

Includes: Test questions following examples, end-of-chapter exercises.

Biochemistry 551 (Online Version) Lab Manual

Author: Lynne PROST

Description: Biochemistry 551 is an integrated lecture, lab and seminar course that covers biochemistry-centered theory and techniques. The course is designed for upper-level undergraduate students majoring in Biochemistry. Students learn how to apply a broad range of biochemical, genetic, and physical techniques to modern biochemical research. Students also learn how to analyze and interpret the primary scientific literature, develop an understanding of the communication of data, and connect biochemical techniques to basic research.

Lectures introduce concepts and theory that are subsequently explored in detail in experiments. The virtual labs are designed to provide experience with techniques that are used in modern biochemical research through interactive online activities. The curriculum incorporates a research project beginning with the PCR amplification and cloning of the HCAII gene, which codes for the enzyme human carbonic anhydrase II (HCAII). As the semester progresses, students explore how to overexpress, purify and assay wild type and mutant HCAII protein. Experiments covered include PCR, spectrophotometry, gel electrophoresis, protein overexpression and purification, enzyme assays and fluorescence spectroscopy. Several times during the semester, at-home lab experiments are incorporated to provide hands-on experience to supplement student understanding of the virtual labs.

Chemistry 109 Fall 2021

Authors: John Moore, Jia Zhou, and Etienne Garand

Description: This online learning system been created specifically to support you in Chemistry 109 at the University of Wisconsin-Madison. It is more than a textbook and includes more than chemistry. We hope that it helps you learn chemistry and learn how to succeed in this and other challenging courses.

Chemistry: Atoms First

This OpenStax textbook was developed with chemistry professors and a pedagogical approach, with Chemistry OpenStax as the foundation. As the name suggests, this text uses an “atoms first” approach to the subject which involves the introduction of atomic and molecular structure at the beginning of the course material. This text has been successfully adopted.

Includes: instructor resources, exercises, solutions, simulations, and summaries.

Chemistry: The Central Science (Map)

This LibreText resource follows the published Chemistry: The Central Science textbook by Brown et al. but is under a Creative Commons license.

Includes: exercises, solutions, summaries, and simulations.

Chemistry: OpenStax

This text was the precursor to the Atoms First book. This text covers the same concepts but through a different approach. This resource has been successfully adopted and adapted.

Includes: instructor resources, student resources, applications, summaries, exercises, and solutions.

CLUE: Chemistry, Life, the Universe and Everything

Authors: Melanie Cooper and Michael Klymkowsky

Description: Chemistry, Life the Universe and Everything (CLUE) is a transformed general chemistry curriculum, developed by an interdisciplinary team of a chemist and a molecular biologist, that aims to bring about evidence-based change in general chemistry. General Chemistry is a gateway course for many students intending on careers in scientific, engineering, and health care-related disciplines. While there have been many attempts to improve the outcomes for these students, little has changed over the past 60 years. Recent transformation efforts have focused primarily on incorporating student engagement techniques into the course, rather than considering what it is that is important for students to learn. CLUE is different. CLUE was developed using a design research approach that focuses on scaffolded progressions around four core ideas: structure and properties, bonding and interactions, energy, and change and stability. The course emphasizes causal mechanistic reasoning in order to help students move beyond knowing that, to knowing how and knowing why chemical phenomena occur.

Exploring the Physical World: Introductory Chemistry and Physics

Authors: N. Gergel-Hackett, Zachary Zintak, and Marin Higgins

Description: This is a physical science text intended for non-science majors that covers introductory chemistry and physics topics. Below are descriptions of the content found under different headings throughout the text, and how it is recommended that the reader approaches these sections.

Check Your Learning – Sections that begin with this subtitle are meant to gauge your understanding of the material. They usually include practice problems or comprehension questions, and it is highly recommended that you attempt to solve these without looking at the answer first.

LINK TO LEARNING – Sections that begin with this subtitle include links to simulations or websites that are included to apply and reinforce your knowledge of the topic. It is recommended that you follow directions (if given) on what to try within the simulations, but also that you investigate and explore the simulations on your own. Try to find concepts in the simulation that make more sense after reading about the physical or chemical science behind it.

Important Equations, Units, Concepts and Formulas can be found in the final section of the text, as well as their respective chapters.

First Year General Chemistry

Author: Michael Mombourquette

Description: Think of learning Chemistry like learning a language.  In language courses, some students will memorize vocabulary and grammar rules and will succeed to a middling grade.  Others will take the language to heart, internalizing nuances and connections to the point that the memorized aspects are second nature and they will be able to go beyond what the prof has taught.  These latter students will have the greatest success.  The same holds in Chemistry.  We want you to do more than just learn a few equations and how to use them.  We want you to be able to answer questions in ways you’ve never seen before.  We want you to be fluent in the language of chemistry.

You will find that topics are often strongly inter-related in this course. If you fail to learn a key concept early in the course, you will find it to be that much harder to grasp a dependent concept later on.  Many students have done well in high school by cramming at the end of the year.  In courses where you simply have to memorize relatively unrelated material. That method may work for you.  In first-year university chemistry, you will face questions on your exams that force you to pull together concepts in ways you’ve never quite seen before in the course.  Without a thorough understanding of why and how each concept works and how multiple concepts are connected, you’ll never be able to pull together the necessary ideas on your exam and you will find yourself “drawing a blank” on your exams far more often than you think possible right now.  In my experience, ‘drawing a blank’ is code for ‘didn’t practice this enough’.

Foundations of Chemical and Biological Engineering I

Authors: Jonathan Verrett, Rosie Qiao, and Rana A. Barghout

Description: The goal of this textbook is to introduce you to the foundational topics of chemical engineering. This textbook will give you a good basic understanding of a number of chemical engineering concepts, which you can take with you as you progress in your engineering degree and career.

General Chemistry – Lecture & Lab

Author: Dolores Aquino

Description: This course provides an opportunity for students to learn the core concepts of chemistry and understand how those concepts apply to their lives and the world around them, meeting the scope and sequence of most general chemistry courses.

Inorganic Chemistry for Chemical Engineers

Authors: Vishakha Monga, Paul Flowers, Klaus Theopold, William R. Robinson, and Richard Langley

Description: This open access book has been specifically adapted for CHEM 250, an interdisciplinary inorganic chemistry course at UBC-V, for Chemical Engineering students. The main objective of this book is to introduce students to the basic principles of inorganic chemistry and link them with current applications relevant to a chemical engineer. It is a comprehensive online resource for 2nd year undergraduate students everywhere as it will be available under the creative commons license and will be widely available in OER catalogues.

CHEM 1114 – Introduction to Chemistry

Authors: Shirley Wacowich-Sgarbi and Langara Chemistry Department

Description: CHEM 1114 – Introduction to Chemistry is designed for a one-semester introductory chemistry course. For many students, this course provides their first introduction to chemistry. As such, this textbook provides an important opportunity for students to learn some of the core concepts of chemistry and understand how those concepts apply to their lives and the world around them. The text has been developed to meet the scope and sequence of most introductory chemistry courses, including an initial emphasis on the skills required (chapter 1 and 2) for the laboratory portion of the course.

Introductory Chemistry – First Canadian Edition

This text is an adaptation of David W. Ball’s Introductory Chemistry open textbook that was developed by a chemistry professor at Vancouver Island University as part of the B.C. Open Textbook Project. This text has been successfully adopted and includes over 20 additional sections.

Includes: instructor resources, exercises, solutions, examples, and summaries.

Introductory Chemistry – 1st Canadian / NSCC ALP Edition

Authors: David W. Ball and Jessie A. Key

Description: The goal of this textbook is not to make you an expert. True expertise in any field is a years-long endeavor. Here I will survey some of the basic topics of chemistry. This survey should give you enough knowledge to appreciate the impact of chemistry in everyday life and, if necessary, prepare you for additional instruction in chemistry. Throughout each chapter, I present two features that reinforce the theme of the textbook—that chemistry is all around you. The first is a feature titled, appropriately, “Chemistry Is Everywhere.” Chemistry Is Everywhere” focuses on the personal hygiene products that you may use every morning: toothpaste, soap, and shampoo, among others. These products are chemicals, aren’t they? Ever wonder about the chemical reactions that they undergo to give you clean and healthy teeth or shiny hair? I will explore some of these chemical reactions in future chapters. But this feature makes it clear that chemistry is, indeed, everywhere. The other feature focuses on chemistry that you likely indulge in every day: eating and drinking. In the “Food and Drink App,” I discuss how the chemistry of the chapter applies to things that you eat and drink every day. Carbonated beverages depend on the behavior of gases, foods contain acids and bases, and we actually eat certain rocks. (Can you guess which rocks without looking ahead?) Cooking, eating, drinking, and metabolism—we are involved with all these chemical processes all the time. These two features allow us to see the things we interact with every day in a new light—as chemistry.

Introductory Chemistry – Lecture & Lab

Author: Jose Nunez

Description: This course provides an opportunity for students to learn the core concepts of chemistry and understand how those concepts apply to their lives and the world around them, meeting the scope and sequence of most general chemistry courses.

Introductory Organic Chemistry

Author: Carol Higginbotham

Description: Introductory Organic Chemistry is intended for use as a text in a single-term organic chemistry course as part of a one-year Introductory Chemistry course series, also known as a General, Organic and Biological Chemistry (GOB) course series. The text was produced with the specific objective of making an openly-available text for the course CH105 Introduction to Chemistry 2: Organic Chemistry at Central Oregon Community College. The audience for this book is likely to include students majoring in fields outside of the Sciences but who need or want some specific knowledge of the subdiscipline of Organic Chemistry. This will include students in pre-health fields, but also possibly students interested in Natural Resources, Agriculture or Business. The objective is to provide students with an exposure to core ideas of the subject without deep involvement in synthesis problems or organic mechanisms. Introduction to Chemistry is a derivative of the open text Organic Chemistry with a Biological Emphasis, by Timothy Soderberg, Associate Professor Emeritus at the University of Minnesota Morris. This text is cut back dramatically from what is offered by the Soderberg text, but includes sections of text and graphics drawn directly from that source.

Introduction to Chemistry

Author: Carol Higginbotham

Description: Introduction to Chemistry is designed for a one-term introductory chemistry course. For many students, this course provides their first and what may be their only academic introduction to chemistry. As such, this textbook provides an important opportunity for students to learn some core concepts of chemistry and understand how those concepts apply to their lives and the world around them.

MIT OpenCourseWare: Chemical Engineering

MIT OpenCourseWare: Chemistry

OCLUE: Organic Chemistry, Life, the Universe & Everything

Authors:Melanie M. Cooper and Michael W. Klymkowsky

Description: The essence of organic chemistry is how carbon atoms interact with other atoms and groups of atoms to produce an astounding array of complex and interesting molecules. The basics of bonding and intermolecular interactions are introduced in the general chemistry version of CLUE (Chemistry, Life, the Universe & Everything), along with how the structure of a molecule affects its properties, how the energy changes associated with chemical and physical changes can be predicted and explained, and how chemical systems can be stabilized or perturbed by changing conditions. These four core ideas (structure-property relationships, bonding and interactions, energy, and stability, and change) are continued on into OCLUE and are deepened and expanded as we discover and explain ever more complex chemical systems.

Organic Chemistry I

Author: Xin Liu

Description: An open textbook that is suitable for the first semester of Organic Chemistry. Basic concepts of the structures and reactivities of organic molecules are covered in this open textbook. Besides the fundamental discussions of organic acids-bases, stereochemistry, IR and NMR, this book also includes the topics of substitution and elimination reactions, radical substitution of alkanes, preparation and reactions of alkenes and alkynes.

PhET: Chemistry

Yale Open Courses


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